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. 2022 Mar 24;10(4):767. doi: 10.3390/biomedicines10040767

Table 2.

Exosome cargo derived from bone microenvironment cells and their role in bone remodeling.

Bone Microenvironment Cell Source Exosome Cargo Role in Bone Remodeling Reference
Endothelial cells Mir-155 Inhibits osteoclast differentiation [49]
Endothelial cells miR-126 Induces Osteogenesis [45]
Endothelial cells miR-27-a Induces Osteogenesis [50]
Dendritic cells miR-335 Induces Osteogenesis [53]
Dendritic cells TGFB1 and IL-10 Inhibits osteoclasts [53]
Macrophages MiR-5106 Induces osteogenesis [56]