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. 2022 Mar 24;10(4):767. doi: 10.3390/biomedicines10040767

Table 3.

MSC-derived exosome miRNA promoting and inhibiting osteogenic differentiation.

MSC Derived microRNA Promoting Osteogenic Differentiation
Tissue Source microRNA References
Human Bone marrow MiR-15-b [86]
Mouse Bone Marrow MiR-25 [87]
Human Bone marrow MiR-101 [88]
Human Bone marrow 22-3p [89]
Human Bone marrow 935 [90]
Human Bone marrow 664-a-5p [91]
Human Adipose 130a-3p [92]
Human Bone marrow 30-a-5p [93]
Human Bone marrow 133a-3p [94]
Rabbit Bone marrow 122-5p [67]
Rat Bone marrow 128-3p [61]
Human Adipose MiR-375 [95]
Human Bone marrow 200-c [96]
Human Bone marrow 373 [97]
Mouse Bone marrow 29-a [98]
Human Bone marrow, Human Amniotic fluid 21 [115]
MSC-derived microRNA inhibiting osteogenic differentiation
Tissue source microRNA References
Human Bone marrow Mir-29-b-3p [99]
Human Periodontal ligament cells MiR-23-b [100]
Human Adipose MiR-218 [101]
Mouse Adipose 223 [102]
Mouse Bone marrow 206 [103]
Mouse Bone marrow 145-a [104]
Human Bone marrow 124 [105]
Rat Bone marrow 103 [106]
Human Bone marrow 144-3p [107]
Mouse Adipose 26-a [108]
Rat Bone marrow MiR-31 [109]
Human Bone marrow 23-a [110,111]
Human Bone marrow 125-b [112]
Human Bone marrow 370-p [113]
Human Bone marrow 221-5p [114,135]
Human Bone marrow 143 [69]
Human bone fragments 135-a-5p [115]
Rat Bone marrow 205 [116]
Mouse Bone marrow 339 [117]
Human Adipose tissue 130-a-3p [92]
Rat Bone marrow 214 [77]