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. 2022 Apr 15;10(4):914. doi: 10.3390/biomedicines10040914

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Volcano plots of lipids in the plasma, ipsi-, and contralateral cortex and subcortex. The x-axes show the log2 difference between groups consisting in n = 16 sham and n = 15 TBI mice. Lipids that were increased in TBI are positive; those that were reduced are negative. The y-axis shows the negative logarithm of the t-test p-value. The dashed line indicates a p-value of 0.01. (A) Plasma. (B) Ctx-ipsi, ipsilateral perilesional cortex. (C) SubCtx-ipsi, ipsilateral subcortical brain. (D) Ctx-contra, contralateral cortex. (E) SubCtx-contra, contralateral subcortical brain. Abbreviations: TG, triacylglycerol; PC, phosphatidylcholine; SM, sphingomyelin; Cer, ceramide; LPC, lysophosphatidylcholine; PI, phosphatidylinositol; PS, phosphatidylserine.