Table 4.

Multivariable-adjusted odds ratios (95% CIs) for breast cancer across quartile categories of DRRDS, stratified by menopausal status.

	Quartiles of DRRDS				P-trend
	Q1 (n = 292)	Q2 (n = 233)	Q3 (n = 283)	Q4 (n = 242)
Breast cancer
No. of cases (%)	168 (24)	155 (22.1)	215 (30.7)	162 (23.1)
No. of controls	124 (35.4)	78 (22.3)	68 (19.4)	80 (22.9)
Crude	1	0.68 (0.47–0.97)	0.42 (0.30–0.61)	0.66 (0.46–0.95)	0.002
Model 1†	1	0.59 (0.40–0.87)	0.34 (0.23–0.51)	0.60 (0.41–0.88)	<0.001
Model 2‡	1	0.56 (0.37–0.83)	0.33 (0.22–0.50)	0.59 (0.39–0.87)	<0.001
Model 3§	1	0.52 (0.34–0.81)	0.35 (0.21–0.51)	0.59 (0.38–0.90)	0.002
Premenopausal
No. of cases	9 (22)	9 (22)	9 (22)	14 (34.1)
No. of controls	30 (19)	37 (23.4)	54 (34.2)	37 (23.4)
Crude	1	0.81 (0.28–2.29)	0.55 (0.19–1.55)	1.26 (0.48–3.31)	0.73
Model 1	1	0.56 (0.18–1.72)	0.33 (0.11–1.00)	0.82 (0.29–2.29)	0.70
Model 2	1	0.59 (0.16–2.34)	0.46 (0.13–1.53)	0.99 (0.32–3.08)	0.88
Model 3	1	0.37 (0.06–2.12)	0.21 (0.04–0.96)	0.76 (0.19–2.96)	0.86
Postmenopausal
No. of cases	115 (37.2)	69 (22.3)	59 (19.1)	66 (21.4)
No. of controls	138 (25.5)	118 (21.8)	161 (29.7)	125 (23.1)
Crude	1	0.70 (0.47–1.03)	0.44 (0.29–0.64)	0.63 (0.43–0.93)	0.001
Model 1	1	0.60 (0.40–0.91)	0.34 (0.22–0.52)	0.57 (0.38–0.87)	<0.001
Model 2	1	0.59 (0.38–0.91)	0.33 (0.21–0.50)	0.55 (0.36–0.85)	<0.001
Model 3	1	0.57 (0.36–0.90)	0.34 (0.22–0.54)	0.57 (0.36–0.90)	0.001

^†Model 1: Adjusted for age and energy intake.

^‡Model 2: Further adjusted for education, residency, family history of breast cancer, physical activity, marital status, smoking, alcohol consumption, supplement use, breast-feeding, and menopausal status.

^§Model 3: Further adjusted for BMI.