Table 2.

Integrated DEGs in MIRI by RRA.

DEGs	Gene names
Upregulated	Timp1, Serpina3n, Lox, Ccl6, Ccl7, Postn, Ccl9, Ccl2, Ctgf, Fn1, Bcl2a1b, Angptl4, Clec4n, Ms4a6d, Nmrk2, Thbs4, S100a6, Cd53, Hmox1, Col3a1, Adam8, Emp1, Ctss, Ltbp2, Sprr1a, Spp1, Cdkn1a, Col1a1, Mmp14, Aldh1a2, Aebp1, Lcn2, Ugdh, Fxyd5, Efhd2, Mpeg1, Lgals3, Col8a1, Lilrb4, Il4ra, Ccl8, Il33, Uck2, Fgl2, Ptprc, Ccr2, Tmem173, Car13, Mt2, Tnc, Snora75, Hp, Fcgr2b, Ch25h, Myo5a, Col1a2, Anxa1, Fcer1g, Fbn1, Alox5ap, Col5a2, Clic1, Thbs1, Ly86, Il1r1, Saa3, Cd68, Cybb, Pla2g4a, Tyrobp, Clec4d, Cxcl5, Nckap1l, Myof, Ifi30, Igsf6, Pdpn, Cd84, Vcan, Emr1, Chil3, Lcp1, Loxl1, P2ry6, Fstl1, Tnfaip6, Col12a1, Tlr13, Adamts2, Fcgr1, Mmp3, Il1b, Selplg, Col5a1, Clec7a, Mki67, Cyth4, Sulf1, C3ar1, Wisp1, Anxa2, Mfap5, Frzb, Apobec1, Nppb, Itgb2, Serpinb1a, Trem2, Ccna2, Loxl2, Retnlg, Loxl3, Soat1, Itgam, Eif1a, Tgfbi, S100a8, Hbegf, Wfdc17, Runx1, S100a9, Fgr, Emb, Bst1, Mmp8, Msr1, Fhl1, Acta1, Wfdc21
Downregulated	Kcnd2, Gpr22, Ldhd, Il15, Ces1d, Kcnip2, 1700040L02Rik, Cdnf, Epm2a, Pfkfb1, Dusp18, A530016L24Rik, Lrrc39, Asb15, Hrasls, Mccc1, Rtn4ip1, Kcnj2, Actr3b, Plxnb1, Tarsl2, Letm2, Fsd2, P2ry1, Dnajc28, Intu, Kcnv2, Ccdc141, Magix, Asb14, Rbm20, Kcnj3, Cmya5, Acacb, Angpt1, Suclg2, Dbt, Wnk2, Rpl3l, Abcc9, Gm10336, Efcab2, Cpeb3, A930018M24Rik, Gca, Slc38a3, Adra1a, Itgb6, Ppm1k, Pdpr, Mylk4, Mettl7a1, Arhgap20, Rnf207, Krt222, Mccc2, Gm31251, Klf9, Epha4, Tcp11l2, Aldh4a1, Efnb3, Akr1c14, Ppp2r3a, Tmem143, Isoc2a, Btnl9, Fyco1, Jmy, Helt, Tcaim, Pank1, Osbpl3, Slc16a10, Klra21, Pkd2l2, Cacna1c, Osbp2, Ppm1l, Cyfip2, Hlf, Gm30307, Lmod3, Slc2a12, Nebl, Pm20d1, Ppara, Mmp15, C1qtnf9, Tmem25, Ank2, Mitf, Colgalt2, Pitpnc1, Mlxipl, Ppargc1b, Lrtm1, Rps6ka2, Apol10b, Dsg2, Ucp3