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. 2001 Feb;45(2):605–607. doi: 10.1128/AAC.45.2.605-607.2001

TABLE 2.

MFCs for germinated and nongerminated conidia of Aspergillus spp.

Species (no. of strains) and antifungal agent MFCa (MFC90) [μg/ml]
Germinated Nongerminated
A. flavus (12)
 Amphotericin B 0.5–2 (2) 0.5–2 (2)
 Itraconazole 0.2–8 (1.0) 0.06–8 (0.5)
 Voriconazole 0.12–8 (2) 0.2–8 (2)
 Posaconazole 0.06–2 (1.0) 0.12–1.0  (1.0)
 Ravuconazole 0.2–4 (4) 0.12–2 (2)
A. fumigatus (30)
 Amphotericin B 0.2–8 (2) 0.5–8 (4)
 Itraconazole 0.2–>8 (8) 0.12–>8 (8)
 Voriconazole 0.06–8 (4) 0.06–>8 (2)
 Posaconazole 0.12–>8 (2) 0.06–>8 (2)
 Ravuconazole 0.5–>8 (>8) 0.2–>8 (>8)
A. nidulans (10)
 Amphotericin B 0.2–8 (1.0) 0.5–8 (1.0)
 Itraconazole 0.12–>8 (0.5) 0.06–>8 (0.5)
 Voriconazole 0.12–2 (1.0) 0.06–2 (1.0)
 Posaconazole 0.03–2 (1.0) 0.06–2 (1.0)
 Ravuconazole 0.06–2 (2) 0.06–2 (1.0)
A. niger (7)
 Amphotericin B 0.5–2 (1.0) 1.0–2 (1.0)
 Itraconazole 0.5–8 (2) 0.2–4 (0.5)
 Voriconazole 0.5–2 (2) 0.2–2 (1.0)
 Posaconazole 0.2–1.0 (0.5) 0.2–0.5 (0.5)
 Ravuconazole 2–>8 (8) 2–>8 (8)
A. sydowii (1)
 Amphotericin B 2 (NDb) 2 (ND)
 Itraconazole >8 (ND) >8 (ND)
 Voriconazole 4 (ND) 2 (ND)
 Posaconazole 2 (ND) 2 (ND)
 Ravuconazole 0.5 (ND) 0.5 (ND)
A. terreus (12)
 Amphotericin B 1.0–4 (4) 1.0–>8 (>8)
 Itraconazole 0.06–8 (2) 0.12–>8 (2)
 Voriconazole 1.0–>8 (>8) 1.0–>8 (>8)
 Posaconazole 0.06–4 (2) 0.12–4 (2)
 Ravuconazole 4–>8 (8) 4–>8 (>8)
a

Fewer than three colonies. 

b

ND, not determined.