Table 1.

Demographics, clinical characteristics, and outcome data of the included patients with traumatic brain injury (TBI) stratified by the Glasgow Coma Scale (GCS), N = 592.

Variables	Initial GCS 14-15 (mild) N = 566	Initial GCS 9-13 (moderate) N = 20	Initial GCS 3-8 (severe) N = 6
Demographics
Age, years, median [IQR]	62 [45;74]	69 [38;76]	41 [35;54]
– > 65 years, n/N (%)	257/566 (45.4)	12/20 (60.0)	1/6 (16.7)
Male, n/N (%)	329/566 (58.1)	13/20 (65.0)	5/6 (83.3)
Clinical characteristics
Charlson comorbidity index
0, n/N (%)	161/566 (28.4)	6/19 (31.6)	3/6 (50)
1–2, n/N (%)	138/566 (24.4)	6/19 (31.6)	2/6 (33.3)
3–4, n/N (%)	159/566 (28.1)	5/19 (26.3)	1/6 (7, 16)
≥5, n/N (%)	108/566 (19.1)	2/19 (10.5)	0/6 (0.0)
Antiplatelet/-coagulant treatment
Yes, n/N (%)	144/556 (25.9)	4/19 (21.0)	0/6 (0.0)
– Acetylsalicylic acid, n/N (%)	65/144 (45.1)	2/4 (50.0)	-
– ADP-receptor antagonist, n/N (%)	32/144 (22.2)	0/4 (0.0)	-
– Vitamin K antagonist, n/N (%)	18/144 (12.5)	2/4 (50.0)	-
– NOAC, n/N (%)	32/144 (22.2)	0/4 (0.0)	-
Trauma mechanism
Traffic, n/N (%)	143/557 (25.6)	4/19 (21.0)	3/6 (50.0)
Fall <2m, n/N (%)	350/557 (62.8)	9/19 (47.4)	2/6 (33.3)
Fall >2m, n/N (%)	17/557 (3.1)	3/19 (15.8)	1/6 (16.7)
Violence, n/N (%)	14/557 (2.5)	0/19 (0.0)	0/6 (0.0)
Other, n/N (%)	33/557(5.9)	3/19 (15.8)	0/6 (0.0)
Additional symptoms
Loss of consciousness and/or amnesia, n/N (%)	142/566 (25.1)	-	-
Vomiting, n/N (%)	23/566 (4.1)	-	-
Suspected intake of alcohol/drugs prior to trauma
Yes, n/N (%)	161/521 (30.9)	6/18(33.3)	3/4 (75.0)
Bone fracture
Yes, n/N (%)	21/566 ()	0/20 (0)	0/6 (0)
CT examination
Yes, n/N (%)	344/566 (60.7)	17/20 (85.0)	5/6 (83.3)
Clinical outcome
Intracranial lesion	32/566 (5.7)	8/20 (40.0)	4/6 (66.7)
– Neurosurgical observation and/or intervention	4/32 (12.5)	5/8 (62.5)	4/4 (100.0)
– Death within 7 days due to TBI	2/566 (0.4)	1/20 (5.0)	0/6 (0.0)

TBI, Traumatic Brain Injury; GCS, Glasgow Coma Scale; IQR, Interquartile range.