Table 2.

S100B concentrations and sampling times in prehospital and in-hospital serum samples from patients with TBI stratified by GCS, N = 592.

	Prehospital			Inhospital
Variable	Initial GCS 14-15 (mild)	Initial GCS 9-13 (moderate)	Initial GCS 3-8 (severe)	Initial GCS 14-15 (mild)	Initial GCS 9-13 (moderate)	Initial GCS 3-8 (severe)
Valid biomarker concentrations	N = 566	N = 20	N = 6	N = 566	N = 20	N = 6
S100B μg/L, mean (95%CI)	0.29 (0.26;0.32)	0.51 (0.24;1.1)	0.81 (0.28;2.3)	0.17 (0.16;0.18)	0.33(0.16;0.70)	0.44 (0.17;1.17)
S100B ≥0.10 μg/L, n/N (%)	484/566 (85.5)	18/20 (90.0)	6/6 (100.0)	398/566 (70.3)	16/20 (80.0)	6/6 (100.0)
Hemolysis Index, mean (95%CI)	0.21 (0.20;0.23)	0.23 (0.12;0.43)	0.42 (0.11;1.6)	0.05 (0.05;0.06)	0.08 (0.04;0.2)	0.06 (0.06;0.19)
Valid sampling times	N = 507	N = 16	N = 5	N = 507	N = 16	N = 5
Minutes from trauma to sampling, median [IQR]	40 [25;75]	47.5 [32;97]	32 [10;49]	106 [82;146]	106 [80;142]	95 [94;103]

TBI, Traumatic Brain Injury; GCS, Glasgow Coma Scale; CI, Confidence interval; IQR, Interquartile range.