Fig. 4.

Constellation of symptoms checklist for cardiac ATTR amyloidosis. Healthcare practitioners should evaluate patients with heart failure with preserved ejection fraction for a clinical history of carpal tunnel syndrome or lumbar spinal stenosis, along with progressive neuropathy or autonomic dysfunction. Clustering of these clinical signs and symptoms should prompt screening for cardiac amyloidosis and trigger referral to a multidisciplinary team at an amyloidosis expert center. ATTR amyloid transthyretin