. 2022 Mar 8;41(5):751–760. doi: 10.1007/s10096-022-04415-6

Table 5.

The effects of the antimicrobial agents benzylpenicillin, cefuroxime and ceftriaxone against 139–141 Aerococcus urinae isolates. Zone diameters (mm), MIC50, MIC90, and MIC ranges are described. The correlation and the number of susceptibility interpretations (S/I/R) between MIC methods are shown

Antimicrobial agent	Disk diffusion mm	Gradient test				Broth microdilution (BMD)				Gradient vs. BMD
		MIC (mg/L)				MIC (mg/L)				Pearson correlation
		MIC₅₀^a	MIC₉₀^b	Range	S/I/R^c	MIC₅₀^a	MIC₉₀^b	Range	S/I/R^c	Pearson correlation
Benzylpenicillin	26–47	0.023	0.032	0.004–0.125	141/0/0	≤ 0.03	0.06	≤ 0.03–0.12	139/0/0	0.428, p < 0.001
Cefuroxime	24–47	0.19	0.5	0.012–2	141/0/0	0.5	2	0.5–4.0	139/0/0	0.622, p < 0.001
Ceftriaxone	23–47	0.38	1.0	0.016–32	129/8/3	0.5	2	0.12– > 2	121/14/4	0.579, p < 0.001

^aMIC value at which ≥ 50% of the isolates are inhibited

^bMIC value at which ≥ 90% of the isolates are inhibited

^cS, susceptible; I, susceptible, increased exposure; R, resistant