Table 5.

Interventions to alleviate financial toxicity.

Study	Number of subjects	Intervention	Outcomes
Knight TG., et al. Prospective, intervention study [71]	105	Group 1 met with a nurse navigator, a clinical pharmacist, and a financial planner to identify and address gaps in coverage, provide financial and budgeting assistance. Group 2 was standard assistance arm.	After adjusting for insurance, race, and age at survey, the risk of death with the intervention was 0.47 times the risk of death in those without the intervention (95% CI 0.23–0.98, p = 0.043).
De Souza JA., et al. Prospective, intervention study [72]	308	Co-pay assistance from the Patient Access Network Foundation, with assessment of financial toxicity over a period of 3 months.	89% had an improvement in financial toxicity over the 3 months.
Albelda R, et al. Retrospective analysis [20]	171	Analysis of the effect of paid leave in the BMT population, on financial burden at 6 months post-transplant.	Paid leave improved financial burden in the post-transplant period when looking at three separate measures of FT (p < 0.05).
Sidana, S., et al. Prospective analysis [73]	123	Assessing financial burden in patients enrolled on clinical trial (n = 34, 28%) versus not on clinical trial (n = 89, 72%) over the first year of treatment.	Patients on clinical trials (CT) reported less need for taking extended time off from work (22% CT vs 46% non-CT p = 0.02). Financial burden was found to be lower in the CT group but differences not statistically significant.
Hong, D., et al. Retrospective analysis [52]	474	Analysis of the rates of treatment abandonment in a province in China, before and after adoption of increased government insurance aid policies.	Abandonment of treatment decreased from 40% (6/15) to 0% (0/6) after new insurance policies were set in place.