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. 2022 Jan 13;100(2):112–126. doi: 10.1111/imcb.12519

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© 2022 The Authors. Immunology & Cell Biology published by John Wiley & Sons Australia, Ltd on behalf of Australian and New Zealand Society for Immunology, Inc.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Differential effects on activation by 6‐formylpterin (6‐FP) and acetyl‐6‐FP (Ac‐6‐FP). (a) Bar graphs showing the mean fluorescence intensity (MFI) of MHC‐related protein 1 (MR1) expression on A375.MR1^HI cells when pulsed with titrating concentrations of 6‐FP or Ac‐6‐FP. (b, c) Bar graphs showing activation of T‐cell receptor (TCR)‐expressing SKW‐3 cells as measured by CD69, after coculture with, (b) A375.MR1^HI cells or (c) A375.MR1^K43A cells, with titrating doses of 6‐FP or Ac‐6‐FP. Points on all plots are replicate wells, and data are representative of two independent experiments. PE, phycoerythrin.