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. 2022 Apr 11;31(5):587–596. doi: 10.1007/s10068-022-01062-7

Fig. 2.

Fig. 2

Fermentation residue of S. cerevisiae reduce melanin contents in B16F10 cells through the inhibition of tyrosinase activity. (A) Cytotoxic effect of fermentation residue of S. cerevisiae on B16F10 cells measured by MTS assay. (B) The effect of fermentation residue of S. cerevisiae on tyrosinase activity was estimated using a mushroom tyrosinase assay. (C) The effect of fermentation residue of S. cerevisiae on cellular tyrosinase activity in α-MSH-induced B16F10 cell was estimated using a cellular tyrosinase assay. (D) The effect of fermentation residue of S. cerevisiae on melanin contents in α-MSH-induced B16F10 cell was estimated using a melanin contents assay. Data are presented as mean ± SD. (*) p < 0.05 and (***) p < 0.001 versus control group (Student’s t-test)