Anti-cholinesterase activities of alkaloids from the tubers of Stephania pierrei^a.

Compounds	AChEb	BuChEc
	IC50 (μM)	IC50 (μM)
1	41.47 ± 0.77	Inactived
2	15.41 ± 0.54	Inactived
3	149.63 ± 1.33	63.12 ± 0.83
11	Inactived	Inactived
12	Inactived	221.16 ± 1.62
13	26.99 ± 0.58	109.33 ± 0.97
14	71.28 ± 1.90	65.35 ± 0.80
15	11.33 ± 0.15	13.52 ± 0.59
17	21.16 ± 0.40	234.34 ± 1.08
18	12.25 ± 0.44	31.46 ± 0.20
19	152.59 ± 0.81	Inactived
21	18.31 ± 1.55	32.82 ± 0.34
22	8.32 ± 0.12	2.85 ± 0.08
23	11.34 ± 0.20	2.80 ± 0.07
24	11.94 ± 0.39	16.58 ± 0.54
25	17.37 ± 0.22	10.51 ± 0.27
26	6.11 ± 0.38	26.41 ± 0.43
27	17.63 ± 0.67	7.42 ± 0.16
28	6.12 ± 0.63	5.87 ± 0.06
29	4.30 ± 0.28	22.47 ± 0.10
30	140.15 ± 0.83	Inactived
32	141.47 ± 0.82	10.08 ± 0.15
33	Inactived	175.55 ± 1.45
34	73.08 ± 0.33	13.60 ± 0.30
35	265.82 ± 0.80	Inactived
36	Inactived	Inactived
38	1.21 ± 0.09	3.34 ± 0.02
39	2.85 ± 0.24	3.26 ± 0.05
40	147.18 ± 0.71	20.32 ± 0.39
41	32.49 ± 0.52	14.11 ± 0.25
42	1.09 ± 0.02	5.57 ± 0.15
43	Inactived	150.57 ± 0.54
44	40.86 ± 0.67	20.46 ± 0.42
45	7.49 ± 0.66	7.83 ± 0.11
Galanthaminee	1.21 ± 0.11	3.59 ± 0.07

^aData represent as IC₅₀ values in μM ± S.D. of three independent experiments.

^bAcetylcholinesterase.

^cButyrylcholinesterase.

^dInactive at 0.1 mg mL⁻¹.

^eGalanthamine was used as the reference drug.