| PCL loaded with OTC–ZnO NPs |
– Develop the PCL–OTC–ZnO nanofibers for use in the treatment of periodontal diseases |
– PCL–OTC–ZnO nanofibers were non-cytotoxic |
133
|
| – The PCL–OTCz nanofibers developed have great potential as a drug delivery system for the PD treatment |
| – PCL–OTCz exhibited excellent activity against a mixed bacterial culture |
| PCL–ZnO NPs |
– Evaluation of the osteoconductivity and antibacterial properties |
– The engineered membrane exerts both osteoconductive and antibacterial properties |
140
|
| – Demonstrating its great potential for periodontal tissue engineering |
| Sealer incorporated with Ag–ZnO NPs |
– Evaluation of the antimicrobial efficacy of ZnO based sealer incorporated with silver and zinc oxide NPs compared with simple zinc oxide sealer against Enterococcus faecalis
|
– After three weeks from obturation, silver NPs had a superior antibacterial effect, but after one week of obturation there was no significant difference between the groups |
141
|
| ZnO NPs |
– Estimate the effect of ZnO NPs on salivary AST activity in chronic periodontitis patients |
– Increasing salivary activity in presence of ZnO NPs |
135
|
| ALP, AST–ZnO NPs |
– Determine of kinetic study of ALP, AST and peroxidase in presence and absence of ZnO NPs in saliva of chronic periodontitis patients |
– The activity of salivary AST was increased in presence of ZnO NPs |
142
|
| – The inhibited effect of ZnO NPs on both salivary ALP and peroxidase activities was confirmed |
| PCL/gelatin–ZnO NPs |
– The synthesis of bioactive scaffolds for periodontal regeneration and \development of a cell-friendly disinfection strategy through the fabrication of drug delivery systems |
– PCL/GEL-based membranes containing a low content of ZnO NPs can potentially function as a biologically safe antimicrobial membrane for guided tissue/bone regeneration with satisfactory cytocompatibility |
139
|
| ZnO NPs–gelatin–PLC membrane |
– Evaluate the antimicrobial capacity and cytocompatibility of ZnO-loaded membranes for periodontal regeneration |
– The mechanical properties of the membranes were reduced upon ZnO incorporation, except for PCL-based membranes containing ZnO at the 30 wt% concentration |
130
|
| – All ZnO-containing membranes displayed antibacterial activity |
| – All membranes synthesized demonstrated satisfactory cytocompatibility, although the presence of 30 wt% ZnO led to decreased viability |
