F68 | ||||
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K (M−1) |
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Cytarabine | ||||
298.15 | (4.8 ± 0.1) × 102 | −(0.4 ± 0.01) | 50.2 ± 1.0 | −(15.3 ± 0.3) |
303.15 | (5.7 ± 0.1) × 102 | −(0.3 ± 0.01) | 51.8 ± 1.0 | −(16.0 ± 0.3) |
308.15 | (8.3 ± 0.2) × 102 | −(0.3 ± 0.05) | 55.0 ± 1.1 | −(17.2 ± 0.3) |
313.15 | (9.3 ± 0.2) × 102 | −(0.3 ± 0.06) | 56.0 ± 1.1 | −(17.8 ± 0.4) |
Gemcitabine | ||||
298.15 | (6.2 ± 0.1) × 103 | 19.1 ± 0.38 | 136.5 ± 2.7 | −(21.6 ± 0.4) |
303.15 | (7.8 ± 0.2) × 103 | 13.5 ± 0.27 | 119.1 ± 2.4 | −(22.6 ± 0.5) |
308.15 | (8.7 ± 0.1) × 103 | 8.7 ± 0.17 | 101.7 ± 2.0 | −(22.6 ± 0.4) |
313.15 | (2.1 ± 0.6 × 103 | 2.1 ± 0.04 | 83.2 ± 1.5 | −(24.0 ± 0.4) |
Hydroxyurea | ||||
298.15 | (4.7 ± 0.1) × 102 | −(0.4 ± 0.1) | 49.8 ± 0.9 | −(15.2 ± 0.3) |
303.15 | (5.2 ± 0.9) × 102 | −(0.4 ± 0.2) | 50.8 ± 1.0 | −(15.3 ± 0.3) |
308.15 | (7.2 ± 0.4) × 102 | −(0.4 ± 0.1) | 53.4 ± 1.1 | −(16.3 ± 0.3) |
313.15 | (7.9 ± 0.5) × 102 | −(0.4 ± 0.1) | 54.2 ± 1.1 | −(17.4 ± 0.3) |