Chemical structures of natural flavanones and IC₅₀ values obtained against mushroom tyrosinase.

Compound no.	Compound name	Chemical structures	IC50 values (μM)	Reference
120	5,5′,7-Trihydroxy-2′,4′-dimethoxy-6-methylflavanone		44.74	68
121	Streppogenin		1.3	68
122	5,7,2′-Trihydroxy-5′-(1′′′,1′′′-dimethylallyl)-8-prenylflavanone		27.5	97
123	Liquiritigenin		22.0	50
124	Bavachinin		143.9	30
125	Corylifolin		23.6	30
126	Alpinetin		450	50
127	Delanin		0.26	144
128	5,7,2′-Trihydroxy-8,3′-diprenylflavanone		68.5	97
129	5,7,2′-Trihydroxy-5'-(1′′′,1′′′-dimethylallyl)-8-prenylflavanone		27.5	142
130	2-(2,4-Dihydroxyphenyl)-7-hydroxychroman-4-one		0.11	4
131	5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-(3-methylbut-2-en-1-yl)chroman-4-one		38.1	4
132	5,7-Dihydroxy-2-(2-hydroxy-4,6-dimethoxy phenyl)-6-methylchroman-4-one		44.74	4
133	7-Hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-en-1-yl)chroman-4-one		77.4	4
134	2-(2,4-Dihydroxyphenyl)-5-hydroxy-7-methoxychroman-4-one		2.0	4
135	2-(2,4-Dihydroxyphenyl)-5,7-dihydroxychroman-4-one		1.76	4
136	5,7-Dihydroxy-2-(4-hydroxy phenyl)chroman-4-one		>300	4
137	(3,4-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy-(4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxyphenyl-7-hydroxychroman-4-one		88.91	4
138	5,7-Dihydroxy-2-phenyl chroman-4-one		>500	4
Standard	Kojic acid		310	4, 30 and 50