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. 2021 Jun 23;11(36):22159–22198. doi: 10.1039/d1ra03196a

Chemical structures of natural flavonols and IC50 values obtained against mushroom tyrosinase.

Compound no. Compound name Chemical structures IC50 values (μM) Reference
139 Quercitin graphic file with name d1ra03196a-u156.jpg 10.73 58
140 Kaempferol graphic file with name d1ra03196a-u157.jpg 5.5 71
141 Galangin graphic file with name d1ra03196a-u158.jpg 3.55 38
142 Rutin graphic file with name d1ra03196a-u159.jpg 130 101
143 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one graphic file with name d1ra03196a-u160.jpg 53.4 31
144 2-(3,4-Dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4H-chromen-4-one1 graphic file with name d1ra03196a-u161.jpg 72.5 31
145 6-Hydroxykaempferol graphic file with name d1ra03196a-u162.jpg 124 31
146 6-Hydroxygalangin graphic file with name d1ra03196a-u163.jpg 182 31
Standard Kojic acid graphic file with name d1ra03196a-u164.jpg 318 31, 38, 58 and 71