Chemical structures of natural flavanols and IC₅₀ values obtained against mushroom tyrosinase.

Compound no.	Compound name	Chemical structures	IC50 values (μM)	Reference
74	Dihydromyricetin		849.88	167
75	Taxifolin		0.24	118
76	Dihydromorin		9.4	10
77	Dihydroxykampherol		>200	58
78	Broussoflavonol J		9.29	96
79	3,5,7-Trihydroxy-2-(4-hydroxyphenyl)chroman-4-one		25	22
80	Chlorophorin		6.6	172
81	Proanthocyanidins		55.01	146
82	4-(3,8-Diacetoxy-5-hydroxy-4-oxochroman-2-yl)-1,2-phenylene diacetate		>230	28
83	3,5,7-Trihydroxy-2-(4-hydroxyphenyl)chroman-4-one		>100	28
84	2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxychroman-4-one		>300	28
85	4-(3,7-Diacetoxy-5-hydroxy-4-oxochroman-2-yl)-1,2-phenylene diacetate		>230	28
86	2-(2-Hydroxyphenyl)-3,5,7-trihydroxychroman-4-one		25	28
87	2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxychroman-4-one		>300	28
88	2-(3,4-Dimethoxyphenyl)-3-hydroxy-5,7-dimethoxychroman-4-one		75.8	28
89	2-(3,4-Dihydroxyphenyl)-3,5-dihydroxy-(7,2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl)oxychroman-4-one		>200	28
90	3,5,7-Trihydroxy-2,7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydrobenzofuran-5-ylchroman-4-one		28.8	28
Standard	Kojic acid		237	28 and 167