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. 2022 Apr 2;60:101491. doi: 10.1016/j.molmet.2022.101491

Figure 6.

Figure 6

Hepatic Sdc4 overexpression does not alter whole body energy homeostasis or glycemic control. (A) Body weight (dotted line indicates Sdc4-AAV or Control-AAV injection), (B) tissue weights, (C) lean and fat mass, (D) daily food intake, (E) energy expenditure, (F) respiratory exchange ratio (RER), (G) glucose tolerance following oral glucose administration (2 g/kg), (H) fasting and glucose-stimulated plasma insulin levels, and (I) blood glucose in response to i.p insulin administration (1 U/kg). (J) Plasma free fatty acids, (K) cholesterol and (L) triglycerides. Data are presented as mean ± SEM, with n = 7–10 per group. ∗P < 0.05 vs. Control-AAV. Significance was assessed by students two tailed unpaired t-test (panels B, C, D, J, K, L) or two-way ANOVA followed by Bonferroni's post hoc test (panels A, E, F, G, H, I).