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. 2022 Apr 22;17(1):781–800. doi: 10.1515/med-2022-0476

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© 2022 Xiang Xu et al., published by De Gruyter

This work is licensed under the Creative Commons Attribution 4.0 International License.

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EMT-related lncRNAs diagnostic signature for CAD. (a) LASSO coefficient profiles of the 16 EMT-related lncRNAs selected by the optimal lambda. (b) The diagnostic signature selection of optimal parameter (lambda) in LASSO model. (c and d) Results of SVM-RFE algorithms: The point highlighted indicates the lowest error rate, and the corresponding EMT-related lncRNAs at this point are the best signature selected by SVM-RFE. (e) Venn diagram of overlap EMT-related lncRNAs selected by LASSO and SVM-RFE algorithms. (f) The ROC curve of predicted outcomes of eight EMT-related lncRNAs diagnostic signature by a logistic regression model. (g) ROC analysis results for eight EMT-related lncRNAs in CAD.