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. 2022 Apr 22;17(1):781–800. doi: 10.1515/med-2022-0476

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© 2022 Xiang Xu et al., published by De Gruyter

This work is licensed under the Creative Commons Attribution 4.0 International License.

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The cis and trans network of the EMT-related lncRNAs. (a) Cis-regulation gene of lncRNA CTD-2089N3.3 in the chromosome. The X-axis represents lncRNA position in chromosome and the Y-axis represents correlation coefficient of lncRNA and the potential “cis” gene. The red line represents the genome width of lncRNA and blue point represents the position of potential “cis” gene. (b) Heatmap of the correlations between eight EMT-related lncRNAs and trans-regulated genes. (c) Venn diagram of 33 “trans” genes regulated by eight EMT-related lncRNAs. (d) The cis and trans network of the eight EMT-related lncRNAs (red) in CAD and their target mRNAs (green). (e and f) KEGG enrichment analysis of 34 cis and trans genes regulated by EMT-related lncRNAs.