Table 5.
Summary of mediation analysis for sleep duration, fibrinogen and cognitive function variables.
| Exposure variable (wave 4) | Mediating variable (wave 6) | Outcome variable (wave 8) | Fully Adjusted Mediation Analysis (Coefficient β, 95 % CI)* | Fully Adjusted Mediation Analysis (Coefficient β, 95 % CI)* | ||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| Women | Men | |||||||
|
| ||||||||
| Sleep duration categories | Fibrinogen | Cognitive function | Indirect effect (ab) | Total effect (c) | Direct effect (C) | Indirect effect (ab) | Total effect (c) | Direct effect (c’) |
| <6 | Verbal fluency | −0.013 (−0.065, 0.024) | −0.055 (−0.870, 0.760) | −0.043 (−0.858, 0.773) | 0.003 (−0.031, 0.041) | −0.109 (−1.049, 0.831) | −0.113 (−1.053, 0.828) | |
| >6-7 | −0.005 (−0.040, 0.026) | 0.551 (−0.250, 1.352) | 0.555 (−0.246, 1.357) | −0.000 (−0.034, 0.026) | 0.008 (−0.844, 0.860) | 0.008 (−0.844, 0.860) | ||
| >7-8 | Reference | Reference | Reference | Reference | Reference | Reference | ||
| >8 | −0.016 (−0.085, 0.035) | 0.407 (−0.916, 1.729) | 0.423 (−0.900, 1.746) | 0.007 (−0.052, 0.078) | −0.910 (−2.606, 0.786) | −0.917 (−2.613, 0.780) | ||
| <6 | Verbal memory: immediate recall | −0.004 (−0.017, 0.005) | −0.186 (−0.389, 0.017) | −0.182 (−0.385, 0.021) | 0.001 (−0.007, 0.011) | −0.178 (−0.400, 0.044) | −0.179 (−0.401, 0.043) | |
| >6-7 | −0.001 (−0.011, 0.007) | 0.035 (−0.165, 0.235) | 0.036 (−0.164, 0.236) | −0.000 (−0.008, 0.007) | −0.079 (−0.280, 0.122) | −0.079) (−0.280, 0.122) | ||
| >7-8 | Reference | Reference | Reference | Reference | Reference | Reference | ||
| >8 | −0.005 (−0.022, 0.007) | −0.010 (−0.340, 0.320) | −0.006 (−0.336, 0.324) | 0.002 (−0.011, 0.019) | −0.335 (−0.734, 0.065) | −0.336 (−0.736, 0.064) | ||
| <6 | Verbal memory: delayed recall | −0.002 (−0.016, 0.009) | 0.003 (−0.243, 0.249) | 0.005 (−0.241, 0.252) | 0.000 (−0.010, 0.009) | −0.343 (−0.611,−0.076) | −0.344 (−0.611, −0.076) | |
| >6-7 | −0.001 (−0.011, 0.007) | 0.184 (−0.059, 0.426) | 0.184 (−0.058,0.427) | 0.000 (−0.008, 0.008) | −0.263 (−0.506,−0.020) | −0.263 (−0.506,−0.020) | ||
| >7-8 | Reference | Reference | Reference | Reference | Reference | Reference | ||
| >8 | −0.003 (−0.022, 0.011) | −0.026 (−0.426, 0.373) | −0.023 (−0.423, 0.376) | 0.000 (−0.017, 0.017) | −0.536 (−1.019, −0.053) | −0.536 (−1.019, −0.053) | ||
| <6 | Time orientation | 0.001 (−0.002, 0.005) | 0.057 (−0.026, 0.139) | 0.056 (−0.026, 0.139) | −0.001 (−0.006, 0.003) | −0.067 (−0.171, 0.037) | −0.066 (−0.170, 0.038) | |
| >6-7 | 0.000 (−0.002, 0.003) | 0.034 (−0.046, 0.115) | 0.034 (−0.047,0.115) | 0.000 (−0.004, 0.004) | −0.002 (−0.096, 0.092) | −0.002 (−0.096, 0.092) | ||
| >7-8 | Reference | Reference | Reference | Reference | Reference | Reference | ||
| >8 | 0.001 (−0.003, 0.006) | −0.121 (−0.254, 0.013) | −0.121 (−0.255, 0.012) | −0.001 (−0.011, 0.006) | −0.125 (−0.312, 0.062) | −0.124 (−0.311, 0.064) | ||
CI = confidence interval.
*
For indirect effect bias-corrected 95% confidence intervals are reported. Significant effects are denoted in bold