Table 2. There is a correlation between sex, tRNA modification abundances, and tRNA-modifying enzyme transcript levels.

Table of regression model values generated by the relationship between sex, tRNA modification abundance, and tRNA-modifying enzyme expression across species. There are 20 enzymes/modifications that are sex associated following linear model trends. The trend was considered sex-associated if the p-value < 0.05.

Gene	Modification	Coefficient	Std. Error	t-value	p-value
PUS3	Ψ	−8.4762	0.8001	−10.594	9.34E-07
PUS1	Ψ	−29.307	4.199	−6.98	3.81E-05
DUS3L	D	−23.302	5.816	−4.007	0.00249
DUS2	D	−6.042	2.592	−2.331	0.04197
TRMT9B	m3U	0.37334	3.43793	0.109	0.91567
TRMT13B	Am	−4.5451	0.6187	−7.346	2.47E-05
ADAT2	I	−0.1946	2.2575	1.076	0.93301
TRMT61A	m1A	−5.525	2.074	−2.663	0.02376
TRMT10A	m1A	−2.197	0.9163	−2.398	0.03746
TRIT1	i6A	−6	2.6791	−2.24	0.04904
METTL6	m3C	−18.2294	2.1163	−8.614	6.13E-06
NSUN3	m5C	−3.9764	0.7025	−5.661	0.00021
TRDMT1	m5C	−4.5451	0.6187	−7.346	2.47E-05
FTSJ1	Cm	−29.278	7.934	−3.69	0.00418
TRMT13A	Cm	−1.9868	0.748	−2.656	0.02406
TRMT44	Um	−0.2357	0.5395	−0.437	0.67152
TRMT11	m2G	−2.861	1.825	−1.568	0.14799
FTSJ1	Gm	−29.278	7.934	−3.69	0.00418
TRMT10C	m1G	−5.098	2.714	−1.878	0.08975
TRMT1	mcm22G	−4.734	3.113	−1.521	0.15933
ELP1	mcm5U	−1.848	1.514	−1.221	0.25026
ELP4	mcm5U	−0.7833	1.3064	−0.6	0.5621
CTU1	mcm5s2U	−1.978	1.712	−1.156	0.27461
URM1	mcm5s2U	9.667	2.145	4.507	0.00113
DTWD1	acp3U	−11.076	1.801	−6.151	0.00011
QTRT1	Q	−6.747	1.977	−3.413	0.00663
QTRT2	Q	−4.8298	0.7702	−6.271	9.25E-05
OSGEPL1	t6A	−3.09186	0.80339	−3.849	0.00322
TP53RK	t6A	−13.535	5.534	−2.446	0.03451