Table 3.
Ratio of the multiplicative factor (95% CI) by which the estimated odds change given a 1-s increase in physical function test for the overweight and obese participants divided by the corresponding multiplicative factor for normal BMI participants for different sex and age categories
| Adjusted odds ratio for scoring on the cognition test | ||||||
|---|---|---|---|---|---|---|
| Male | Female | Male, 50-65 yr | Male, > 65 yr | Female, 50-65 yr | Female, > 65 yr | |
| Verbal Memory (CVLT) | ||||||
| Overweight | 1.051 (0.994, 1.112) | 1.031 (0.976, 1.089) | 1.002 (0.924, 1.085) | 1.063 (0.972, 1.163) | 1.064 (0.975, 1.161) | 1.012 (0.934, 1.096) |
| Obese | 1.056 (1.000, 1.115) | 1.029 (0.980, 1.081) | 1.004 (0.921, 1.096) | 1.122 (1.035, 1.217) | 1.022 (0.940, 1.111) | 1.023 (0.956, 1.094) |
| Cognitive Reserve (Spot-the-Word) | ||||||
| Overweight | 1.032 (0.974, 1.094) | 1.054 (0.993, 1.118) | 1.017 (0.933, 1.109) | 1.063 (0.972, 1.161) | 1.069 (0.976, 1.172) | 1.052 (0.959, 1.155) |
| Obese | 1.026 (0.975, 1.081) | 1.070 (1.016, 1.127) | 1.020 (0.930, 1.118) | 1.031 (0.962, 1.106) | 1.089 (0.998, 1.189) | 1.062 (0.985, 1.145) |
| Processing Speed (Symbol–Digit Modalities Test) | ||||||
| Overweight | 1.001 (0.972, 1.030) | 0.989 (0.958, 1.021) | 0.998 (0.953, 1.045) | 0.966 (0.927, 1.007) | 0.985 (0.938, 1.034) | 1.000 (0.948, 1.054) |
| Obese | 1.011 (0.983, 1.040) | 0.998 (0.969, 1.027) | 1.026 (0.976, 1.078) | 1.004 (0.968, 1.042) | 0.980 (0.935, 1.027) | 1.006 (0.961, 1.053) |
| Global Cognition (Mini Mental State Exam) | ||||||
| Overweight | 0.987 (0.879, 1.109) | 1.008 (0.874, 1.163) | 0.840 (0.630, 1.121) | 0.992 (0.873, 1.129) | 1.024 (0.731, 1.434) | 0.986 (0.832, 1.169) |
| Obese | 1.157 (1.012, 1.322) | 1.009 (0.894, 1.137) | 0.960 (0.732, 1.258) | 1.233 (1.049, 1.449) | 1.090 (0.803, 1.479) | 0.988 (0.860, 1.136) |
The results presented are OR (95%CI) for Model C adjusted for sex, age, smoking status, total physical activity, cardiovascular disease risk, type 2 diabetes status, education, depression, alcohol intake, SF-36 mental and physical component scores. The reference category is participants with normal BMI.* P < 0.050. The sample size for each stratification is given below
Verbal memory test -Total sample: 2337; Male: 1037; Female: 1300; Male 50–65 yrs: 615; Male > 65 yrs: 422; Female 50–65 yrs: 800; Female > 65 yrs: 500
Spot-the-Word -Total sample: 2299; Male: 1017; Female: 1282; Male 50–65 yrs: 607; Male > 65 yrs: 410; Female 50–65 yrs: 792; Female > 65 yrs: 490
Symbol–Digit Modalities Test -Total sample: 2341; Male: 1035; Female: 1306; Male 50–65 yrs: 614; Male > 65 yrs: 421; Female 50–65 yrs: 802; Female > 65 yrs: 504
Mini Mental State Exam -Total sample: 967; Male: 442; Female: 525; Male 50–65 yrs: 154; Male > 65 yrs: 288; Female 50–65 yrs: 171; Female > 65 yrs: 354