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. 2022 Apr 23;22:153. doi: 10.1186/s12890-022-01953-9

Table 4.

Patterns of top and selected classes and medications use

All patients (N = 11,204) Autoimmune conditions (N = 2,465)
Baseline
n (%)
Follow-up
n (%)
Baseline
n (%)
Follow-up
n (%)
Percentage of patients with at least one prescription for most common classes of medications
 Adrenal cortical steroids 6502 (58.0) 6999 (62.5) 1737 (70.4) 1842 (74.7)
 Analgesics 6083 (54.3) 5847 (52.2) 1550 (62.8) 1494 (60.6)
 Bronchodilators 5857 (52.3) 6104 (54.5) 1262 (51.2) 1299 (52.7)
 Antihyperlipidemic agents 5620 (50.2) 5644 (50.4) 1053 (42.7) 1085 (44.0)
 Beta-adrenergic blocking agents 4446 (39.7) 4671 (41.7) 809 (32.8) 889 (36.0)
 Proton pump inhibitors 4438 (39.6) 4831 (43.1) 1143 (46.3) 1223 (49.6)
Percentage of patients with at least one prescription for selected classes of medications
 Oral corticosteroids 5135 (45.8) 6,750 (60.2) 1,448 (58.7) 1,690 (68.5)
 Non-biological DMARDs 2596 (23.2) 2,973 (26.5) 1,070 (43.4) 1,130 (45.8)
 Immunomodulators 485 (4.3) 891 (7.9) 320 (13.0) 568 (23.0)
 Biological DMARDs 455 (4.1) 551 (4.9) 296 (12.0) 335 (13.6)
Percentage of patients with at least one prescription for selected medications
 Adalimumab 59 (0.5) 53 (0.5) 52 (2.1) 46 (1.9)
 Azathioprine 218 (1.9) 372 (3.3) 151 (6.1) 246 (10.0)
 Cyclophosphamide 20 (0.2) 31 (0.3) 9 (0.4) 14 (0.6)
 Etanercept 46 (0.4) 41 (0.4) 42 (1.7) 38 (1.5)
 Intravenous immunoglobulin 80 (0.7) 126 (1.1) 34 (1.4) 45 (1.8)
 Infliximab 27 (0.2) 18 (0.2) 25 (1.0) 16 (0.6)
 Methotrexate 372 (3.3) 309 (2.8) 314 (12.7) 238 (9.6)
 Mycophenolate mofetil 244 (2.2) 470 (4.2) 170 (6.9) 320 (13.0)
 Rituximab 35 (0.3) 107 (1.0) 22 (0.9) 67 (2.7)
 Tacrolimus 84 (0.7) 124 (1.1) 23 (0.9) 33 (1.3)