. 2022 Apr 22;22:396. doi: 10.1186/s12879-022-07382-7

Table 1.

Inclusion and Exclusion criteria for selecting DNF patients

Inclusion criteria	Exclusion criteria
1. All patients diagnosed with DFUs met the diagnostic criteria of the 2020 International Working Group on the Diabetic Foot (IWGDF) guidelines 2. All patients with NF met the following diagnostic criteria: 1) extensive necrosis of the superficial fascia with widespread destruction of surrounding tissue; 2) absence of muscle involvement; 3) no clostridium was present in wound and blood cultures; 4) absence of major vascular occlusion; 5) pathological examination of debridement tissue: extensive leukocyte infiltration, focal necrosis of fascia and adjacent tissues, and microvascular thrombosis 3. All patients underwent surgery to clear necrotic tissue	1. Patients with other infectious diseases; 2. No bacterial susceptibility tests were excluded; 3. Patients with necrotizing fasciitis of the head, neck, trunk, or other sites were excluded

Inclusion criteria

Exclusion criteria

1. All patients diagnosed with DFUs met the diagnostic criteria of the 2020 International Working Group on the Diabetic Foot (IWGDF) guidelines

2. All patients with NF met the following diagnostic criteria:

1) extensive necrosis of the superficial fascia with widespread destruction of surrounding tissue;

2) absence of muscle involvement;

3) no clostridium was present in wound and blood cultures;

4) absence of major vascular occlusion;

5) pathological examination of debridement tissue: extensive leukocyte infiltration, focal necrosis of fascia and adjacent tissues, and microvascular thrombosis

3. All patients underwent surgery to clear necrotic tissue

1. Patients with other infectious diseases;

2. No bacterial susceptibility tests were excluded;

3. Patients with necrotizing fasciitis of the head, neck, trunk, or other sites were excluded