Figure 5.

Data from example participants where Ganglion Cell Analysis (GCA) deviation maps did not completely describe reductions in GCIPL thickness with corresponding VF defects, resulting in apparent improved agreement with GCIPL data from non-displaced locations. Panomap data, where retinal nerve fiber layer (RNFL) and GCIPL maps are stitched together, were obtained directly from Cirrus OCT review software. Numerical data overlying the GCA deviation maps are pattern deviation data (dB). (A) The RNFL wedge defect (red outline) is contiguous with the optic disc from Panomap and GCIPL thickness data, but this is not reflected in the deviation map. As such, there is apparent structure-function discordance with Drasdo displacement (numbers highlighted in white), where the deviation map has not flagged abnormal structure within the wedge defect, although these fall within the flagged locations without displacement. (B) The global reduction in GCIPL thickness, more pronounced within the RNFL wedge defect (red outline), is not reflected by the deviation map, which has flagged more marked loss centrally. As such, there is apparent structure-function discordance with Drasdo displacement at relatively peripheral locations (numbers highlighted in white), although these fall within the flagged regions without displacement. However, this does not appear to be indicative of improved concordance without displacement, as more peripheral VF results also do not concord with GCIPL data at these locations (numbers highlighted in orange).