Figure 2.

T2DM inhibits skin cells proliferation. (a) Representative photos of PCNA in the skin. (b) T2DM decreased the PCNA expression in hair follicles (control 13.31 ± 3.428 vs. T2DM 8.462 ± 5.272, brown area %, P = 0.0204, n = 5) and epidermis (control 14.4 ± 3.387 vs. T2DM 9.2 ± 5.45, brown dot per 100 μm, P = 0.0387, n = 5). (c) Representative photos of K14 and DAPI staining in skin. (d) T2DM reduced the depth of K14 in hair follicles (control 525.8 ± 250.5 vs. T2DM 212.2 ± 36.23, μm, P = 0.0353, n = 5). ∗P < 0.05.