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Effect of oridonin on tubular cell apoptosis. (a) TUNEL assay on kidney sections. Scale bar = 10 μm. To detect nuclei, DAPI was used. (b) Number of TUNEL-stained nuclei per field. (c) Western blotting of cleaved caspase-3. (d) Quantification of Western blot results for cleaved caspase-3. n = 8 per group. ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001.
