Skip to main content
. 2021 Sep 13;141(3-4):495–504. doi: 10.1007/s00439-021-02338-4

Table 2.

Comparison of genetic outcomes and clinical characteristics between URM (Black and Hispanic) and control (Asian and White) groups

White/Asian Black/Hispanic p value
Number of variants per child (mean, SD) 3.8 (2.1) 3.6 (2.1) 0.47
% P/LP variants 23.6 15.1 0.002
VUS (%) 76.4 84.9  < 0.001
% of VUSs that are predicted deleterious 38.7 38.1 0.78
Definite genetic diagnosis (%) 37.1 10.3  < 0.001
Possible genetic diagnosis (%) 41 38.1 0.72
% Bilateral 79.6 80.1 1.00
% Severe/profound 23.7 24.5 0.55
% Congenital 37.3 31.6 0.60
% With comorbidities 15.5 20.5 0.34
% Publicly insured 68.1 88.4  < 0.001
% Non-English-speaking 42.0 46.2 0.26

p values from one-way ANOVA