Fig. 2.

A Responsible genes in each age group (congenital/6–39 y.o./over 40 y.o.). B Responsible genes found in autosomal dominant (AD) and autosomal recessive (AR) patients. Among 89 GJB2-associated hearing loss cases identified from autosomal dominant families, 23 carried autosomal dominant inheritance variants and 66 carried biallelic autosomal recessive variants (pseudo-dominant cases). Similarly, among 75 MYO7A-associated hearing loss cases identified from autosomal dominant families, 71 carried autosomal dominant inheritance variants and only 4 carried biallelic autosomal recessive variants (pseudo-dominant cases). C Responsible genes found in groups classified by severity of HL. It was revealed that the types of genes differed according to severity