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. Author manuscript; available in PMC: 2023 May 1.
Published in final edited form as: J Mol Cell Cardiol. 2022 Mar 3;166:107–115. doi: 10.1016/j.yjmcc.2022.02.007

Figure 1.

Figure 1.

miRs regulate cardiac electrophysiology and heart rhythm through two different mechanisms: canonical posttranscriptional RNAi mechanism to regulate the expression of ion channels, which needs hours to days to take effect, and the biophysical modulation to directly and quickly (seconds to minutes) change the dynamics of ion channels.