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. 2022 Apr 23;12:6666. doi: 10.1038/s41598-022-10577-2

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Treatment effects on NAFLD Activity Score and fibrosis stage. (A) Change in mean non-alcoholic fatty liver disease activity score (NAS). Significance is vs. ALT-801 10 nmol/kg. (B) Change in individual NAS. (C) Change in mean fibrosis stage. (D) Change in individual fibrosis stages. The points at each scoring step are slightly shifted to allow visual separation of the animals. This presentation is only for visualization purposes and does not reflect any difference in score. ****p < 0.0001.