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. 2022 Apr 23;12:6694. doi: 10.1038/s41598-022-10600-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Regional distribution of the median value for the trabecular microstructural parameters evaluated in OA (green) and non-OA (blue) patients. No significant differences were found when subchondral trabecular in different anatomical regions were compared within the OA patients. (¤ and ¤¤) shows there is a significant difference between quadrants 1 and 2, and 2 and 3 respectively in non-OA patients. (*) shows a significant difference between OA and non-OA patients (p < 0.05). BV/TV: bone volume fraction; BS/BV: bone specific surface; Tb.Th: trabecular thickness, Tb.Sp: trabecular separation; Tb.Pf: trabecular pattern factor; TMD: tissue mineral density.