Table 5.
Biosensing application of cerium oxide nanoparticles
| S. No | Size of CeNPs | Immobilizing enzyme | Method of immobilization | Biosensor | Observation | Reference |
|---|---|---|---|---|---|---|
| 1 | 30 nm | Nicotinamide adenine dinucleotide and lactate dehydrogenase | Electrodeposition | Lactate | Fabricated biosensor exhibits high sensitivity (571.19 µA mM−1) and linearity range of 0.2–2 mM | Nesakumar et al. (2013) |
| 2 | 34 nm | Cholesterol oxidase | Sol–gel | Cholesterol | The developed biosensor was cost-effective, more sensitive, and highly stable chemically with a linearity range of 0.2–2 mM | Ansari et al. (2008) |
| 3 | 90 nm | Glucose oxidase | Electrodeposition | Glucose | The developed sensor had good sensitivity ranging from 208 − 2290 μA/cm2 mM and the lowest detection limit of 1 nM | Fallatah et al. (2019) |
| 4 | 110 nm | Glucose oxidase | Pulsed laser deposition | Glucose | The developed biosensor showed good linearity of 25–300 mg/dL | Saha et al. (2009) |
| 5 | 35 nm | Lipase | Sol–gel | Triglyceride | They reported that the developed biosensor showed excellent linearity (50–500 mg/dL) and shelf life of 32.8 mg/dL | Solanki et al. (2009) |
| 6 | 90 nm | Cholesterol oxidase | Electrogenerated chemiluminescence | Cholesterol | The developed cholesterol biosensor had linearity of 12–7.2 mM and a detection limit of 4.0 μM | Zhang et al. (2013a) |
| 7 | 3.3 nm | Xanthine oxidase | Sol–gel | Hypoxanthine | The developed hypoxanthine biosensor had a detection limit of 15–89 μM and linearity ranging between 597 and 800 μM | Mustafa et al. (2021) |
| 8 | 40–45 nm | Horseradish peroxidase | Physisorption | Hydrogen Peroxide | The developed biosensor showed Michaelis–Menten constant as 2.21 μM, and linearity ranging from 1.0–170 μM | Ansari et al. (2009) |
The type of immobilizing enzyme, method of immobilization, type of developed biosensor with their characteristics are summarized in the table