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. 2001 Mar;45(3):660–663. doi: 10.1128/AAC.45.3.660-663.2001

TABLE 1.

Numbering of the important class B residuesa

β-Lactamase Zn1 ligands Zn2 ligands
Subclass B1
 Consensus BBL His116 His118 His196 Asp120 Cys221 His263
 BcII His86 His88 His149 Asp90 Cys168 His210
 IMP-1 His77 His79 His139 Asp81 Cys158 His197
 CcrA His99 His101 His162 Asp 103 Cys181 His223
 VIM-1 His88 His90 His153 Asp92 Cys172 His214
 BlaB His76 His78 His139 Asp80 Cys158 His200
 IND-1 His96 His98 His159 Asp100 Cys178 His220
Subclass B2
 Consensus BBL Asn116 His118 His196 Asp120 Cys221 His263
 CphA Asn69 His71 His148 Asp73 Cys167 His205
 Sfh-I Asn72 His74 His151 Asp76 Cys170 His212
Subclass B3
 Consensus BBL His/Gln116 His118 His196 Asp120 His121 His263
 L1 His84 His86 His160 Asp88 His89 His225
 FEZ-1 His71 His73 His149 Asp75 His76 His215
 GOB-1 Gln80 His82 His157 Asp84 His85 His213
 THIN-B His105 His107 His185 Asp109 His110 His253
a

For CcrA, the numbering is reported in references 10 and 24. When not confirmed by a three-dimensional structure, the ligands are underlined. The consensus (bold) and putative consensus (bold and underlined) ligand numbers are given for each subgroup.