Fig. 1.

ADAMTS7 autocleavage sites detected in TAILS experiments.A, ADAMTS7 protein domains and locations of the TAILS significantly regulated WT/EQ peptides indicating autocleavage events. B, ADAMTS7 autocleavage peptide total intensities pooled from all TAILS experiments to show the relative abundance of each event. ADAMTS7, A disintegrin and metalloproteinase with thrombospondin motifs 7; Cys-rich, cysteine-rich; Dis, disintegrin; PL, protease and lacunin; T, thrombospondin repeats; TAILS, terminal amine isotopic labeling of substrates.