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. 2022 Feb 2;388(2):417–438. doi: 10.1007/s00441-022-03593-1

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© The Author(s) 2022

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Fig. 12 — Representative transmission electron images of ultra- sections in CP rat lung, a. shows alveolar lumen (AL) lining with pneumocyte type II (PII) that have irregular heterochromatic nucleus (n) with degenerative changes of its lamellar bodies (*Lb) and atypical vacuolation (v). Macrophage (M) with irregular nucleus (n) and multiple vacuolation in its cytoplasm can be observed. Numerous congested blood capillaries (bc) containing red blood cells (RBCs) and RBCs inside the alveolar lumen (AL) can be noticed. b. shows thick interalveolar septa with multiple interstitial cells (ic), some has irregular elongated heterochromatic and dark stained nuclei (n) and other have round heterochromatic nuclei (N) with multiple vacuolation (V) and collagen fibres deposition. Pneumocyte type II (PII) with euchromatic nuclei (N) and degenerative changes of its lamellar bodies (*Lb) can be observed