Table 2.

Effect of alogliptin treatment on MDA, reduced GSH and TAO levels in lung tissue homogenates

Groups	MDA levels (nmol/mg protein)	GSH (nmol/mg protein)	TAO (mg/gm protein)
Control	7.7 ± 0.34	41.83 ± 1.87	26.5 ± 2.23
ALO	7.5 ± 0.34	40 ± 0.77	27.5 ± 1.9
CP	47 ± 1.67 *	17 ± 0.43 *	13.37 ± 0.42 *
ALO + CP	21.02 ± 2.16*#	31.3 ± 1.4*#	22 ± 0.7 #

Data are represented as the means ± standard error of mean (SEM); analyzed by One-way ANOVA followed by Tukey’s multiple comparisons test. A level of probability (P value) ≤ 0.05 was considered significant. * Significant versus control group; # significant versus CP-treated group. CP cyclophosphamide, ALO alogliptin, TAO total antioxidants, MDA malondialdehyde, GSH reduced glutathione