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. 2022 Mar 23;414(12):3653–3665. doi: 10.1007/s00216-022-04006-6

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Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Venn diagram showing the numbers of infection markers found. Many more infection markers were found to be enriched when comparing bisex-infected with control samples than with monosex-infected samples (A). The same holds for depleted infection markers (B). The terms “enriched” and “depleted” have to be used carefully since further biological analysis is needed to verify that the eggs actually take up and metabolize the lipids. Here, the terms are meant to describe changes in signal intensities found in LC–MS/MS measurements