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. 2022 Apr 11;9:876639. doi: 10.3389/fcvm.2022.876639

FIGURE 1.

FIGURE 1

Intimal hyperplasia. In the healthy vessel (left), the inner intimal layer is composed only of the endothelium (pink layer). Under the endothelium sits the basement layer and internal elastic lamina (IEL). The media layer is composed of elastic fibers and smooth muscle cells (SMC). The outer part of the media and adventitia are separated by the exterior elastic lamina (EEL). Restenosis following vascular surgery is the formation of a neointima layer between the IEL and endothelium. It is composed of proliferating SMC-like cells of different origin and extracellular matrix (ECM).