TABLE 1.
Clinical characteristics of the TRAFIC study population.
| no CAD (n = 67) | CAD (n = 179) | ACS (n = 61) | |
| BMI (kg/m2) | 27.6 ± 4.5 | 27.6 ± 4.4 | 28.3 ± 4.3 |
| Age (years) | 62.5 ± 8.7 | 65.7 ± 8.3* | 64.3 ± 8.9 |
| CRP (mg/L) | 3.2 ± 10.6 | 3.6 ± 8.6### | 17.6 ± 40.7§§§ |
| Creatinine (mg/dL) | 0.9 ± 0.2 | 1.1 ± 0.7** | 1.0 ± 0.3§§ |
| Prior MI (%) | 0.0 (0) | 40.2 (72)*** ## | 20.0 (12)§§§ |
| Sex (% male) | 64.2 (43) | 84.4 (151)** | 77.1 (47) |
| Diabetes Mellitus Type 2 (%) | 9.0 (6) | 25.1 (45)** | 27.9 (17)§ |
| Smoking (%) | 32.8 (22) | 52.0 (93)*,## | 72.1 (44)§§§ |
| Serum Glucose (mg/dL) | 111 ± 21 | 120 ± 39 | 121 ± 32 |
| HbA1c (%) | 5.9 ± 0.6 | 6.2 ± 0.8 | 6.4 ± 0.9 |
| Leukocytes (x106/mL) | 6.8 ± 1.8 | 7.0 ± 2.1### | 8.8 ± 3.1§§§ |
| Total Cholesterol (mg/dL) | 199 ± 42 | 181 ± 42* | 195 ± 51 |
| Triglycerides (mg/dL) | 127 ± 69 | 162 ± 99 | 166 ± 107 |
| LDL (mg/dL) | 116 ± 31 | 99 ± 34* | 99 ± 43 |
| VLDL (mg/dL) | 30.0 ± 15.2 | 34.9 ± 17.7 | 39.7 ± 19.9§ |
| HDL (mg/dL) | 53.7 ± 16.1 | 45.3 ± 13.3* | 47.7 ± 18.5 |
| Arterial Hypertension (%) | 55.2 (37) | 74.3 (133)** | 77.1 (47)§ |
| Hypercholesterolemia (%) | 19.4 (13) | 51.4 (92)*** | 47.5 (29)§§§ |
| Obesity (%) | 22.4 (15) | 25.7 (46) | 27.9 (17) |
| Metabolic Syndrome (%) | 32.8 (22) | 52.5 (94)** | 57.4 (35)§§ |
Categorical variables are expressed in percentages within the groups (total number depicted in brackets), continuous variables as mean ± SD. Statistical significance was tested using Kruskal–Wallis test followed by multiple comparisons for continuous variables, using Fisher’s exact test for categorical variables. MI, myocardial infarction.
*Indicates significance between no CAD and CAD (*p < 0.05, **p < 0.01, ***p < 0.001).
§indicates significance between no CAD and ACS (§p < 0.05, §§p < 0.01, §§§p < 0.001).
#indicates significance between CAD and ACS (#p < 0.05, ##p < 0.01, ###p < 0.001).