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. 2022 Apr 11;9:848463. doi: 10.3389/fmolb.2022.848463

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Copyright © 2022 Chen, Meng, Yan, Wang, Jiang and Gao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Establishment of a LASSO model for distinguishing SLE from normal controls. (A) Ten-fold cross-verification of turning parameter selection in the LASSO model. (B) LASSO coefficient profiling of the hub genes. (C) Box plots show the expression of characteristic genes in SLE and normal PBMCs in the GSE50772 dataset. (D) Verification of the expression of characteristic genes in SLE and normal PBMCs in the GSE81622 dataset. ***p < 0.001.