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. 2022 Apr 11;9:848463. doi: 10.3389/fmolb.2022.848463

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Copyright © 2022 Chen, Meng, Yan, Wang, Jiang and Gao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Activation of inflammatory response in SLE and up-regulation of TK1 in SLE BMSCs. (A–F) Serum levels of (A) IFN-γ, (B) IL-12, (C) IL-6, (D) IL-13, (E) IL-18 as well as (F) IL-1β were measured in twenty SLE patients and twenty controls through ELISA. (G–I) TK1 mRNA expression was tested in BMSCs from five SLE patients and five controls through (G) RT-qPCR and (H,I) western blotting. ***p < 0.001; ****p < 0.0001.