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. 2022 Apr 11;12:782030. doi: 10.3389/fonc.2022.782030

Table 3.

Multivariate logistic regression models for different recurrence sites and subtypes.

Subgroup Reference LR DM LNR Organ recurrence
OR (95CI) P OR (95CI) P OR (95CI) P OR (95CI) P
Tumor size
>=4cm <4cm 1.308 (0.808~2.118) 0.274 1.012 (0.558~1.835) 0.970 1.016 (0.563~1.833) 0.958
Lymph nodes
N+ N− 1.159 (0.670~2.005) 0.598 1.622 (0.962~2.735) 0.070 3.729 (1.838~7.563) <0.001 1.559 (0.791~3.072) 0.200
SCCA
>=2.55 <2.55 1.265 (0.739~2.164) 0.392 1.127 (0.678~1.872) 0.645 1.509 (0.762~2.991) 0.238 3.690 (1.838~7.407) <0.001
DSI
>=1/2 <1/2 2.026 (1.172~3.502) 0.011 1.792 (0.908~3.534) 0.093 1.698 (0.509~5.682) 0.388 1.743 (0.532~5.709) 0.358
LVSI
Positive Negative 1.747 (0.763~4.001) 0.187 1.931 (1.153~3.235) 0.012 2.140 (0.936~4.893) 0.071 2.367 (1.154~4.919) 0.002
Parametrial
Positive Negative 1.293 (0.671~2.490) 0.443 1.212 (0.618~2.377) 0.576 1.191 (0.591~2.397) 0.625 1.143 (0.572~2.287) 0.705
ART
Yes No 0.148 (0.075~0.291) <0.001 2.401 (1.470~4.543) <0.001 0.650 (0.212~1.993) 0.451
Chemotherapy
Yes No 0.519 (0.31~0.869) 0.043 1.078 (0.373~3.114) 0.890 0.895 (0.312~2.567) 0.837

SCCA, squamous cell carcinoma antigen; LVSI, lymph-vascular space invasion; DSI, deep stromal invasion; ART, adjuvant radiotherapy.