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Paternal high-fat diet leads to gluconeogenesis alteration in offspring. (A,B) Glucose tolerance test (2 g/kg body weight) and AUC of 11-week-old CD-F1 (n = 7) and HFD-F1 (n = 7) male mice. (C,D) Insulin tolerance test (1 IU/kg body weight) and AUC of 12-week-old CD-F1 (n = 7) and HFD-F1 (n = 7) male mice. (E,F) Pyruvate tolerance test (2 g/kg body weight) and AUC of 13-week-old CD-F1 (n = 7) and HFD-F1 (n = 7) male mice. *p < 0.05, **p < 0.01, ***p < 0.001.
