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. 2022 Apr 11;12:809407. doi: 10.3389/fcimb.2022.809407

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Copyright © 2022 Morris, Luo, Sachithanandham, Li, Schwartz, Gaston, Gniazdowski, Giraldo-Castillo, Amadi, Norton, Wright, Klein, Pekosz and Mostafa

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Genomic changes in prolonged viral shedding by vaccination and immune status. Substitutions and deletions in 75 patients by status: vaccinated (N =17, A–C) and immunosuppressed (N=44, D–F). (A, D) Barplots with overlayed strip plots of mean time of prolonged shedding of complete genomes in each group, (B, E) Barplots with overlayed strip plots of amino acid change frequency in each group, (C, F) Scatterplots of the correlation of amino acid change and the days after the first positive in each group. *p < 0.05. Unvax, unvaccinated; Vax, vaccinated.