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. 2022 Apr 11;9:880326. doi: 10.3389/fmed.2022.880326

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Copyright © 2022 Tian, Long, Hao, Li, Li, Tang, Li, Zhao, Chen and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CAFs related gene module was identified by WGCNA. (A) The test of scale independence and mean connectivity for constructing scale-free network. (B) Hierarchical clustering dendrogram of co-expressed genes after module fusion. (C) Eigengene dendrogram of function module. (D) Eigengene adjacency correlation heatmap of the function module. (E) Heatmap of the correlation between module and trait. (F) Correlation scatter plot of gene significance for CAFs and module membership from green module. WGCNA, Weighted gene co-expression network analysis.