Fig. 11.

Predicted negative correlation with anti-Diphtheria antibodies titers of in silico children patient cohorts (at age of 5 years) exposed to different PFOS and PFOA concentrations after diphtheria immunization. These in silico predictions mirror the in vivo observed results depicted in Grandjean’s work, indicating that elevated exposures to perfluorinated compounds are associated with reduced humoral immune response to routine childhood immunizations.